Journal of The Korean Society of Clinical Toxicology

Dong-Wun Shin

4 Articles

A Case of Intoxication of Ingested Formalin: Seon-Hee Baek, Kyung-Hwan Kim, Jun-Seok Park, Dong-Wun Shin, Jun-Young Roh, Kyoung-Mi Lee, Ah-Jin Kim; J Korean Soc Clin Toxicol. 2009;7(1):38-40. Published online June 30, 2009

Abstract PDF: Formalin is a water-soluble, colorless, pungent, irritating and highly reactive gas. A 40% solution of formaldehyde in water, also known as formalin, is used as a disinfectant, antiseptic, deodorant, tissue fixative and embalming fluid. Ingestion can lead to immediate deleterious effects on almost all systems of the body including gastrointestinal tract, central nervous system, cardiovsacular system and hepato-renal system, causing gastrointestinal hemorrhage, cardiovsacular collapse, unconsciousness or convulsions, severe metabolic acidosis and acute respiratory distress syndrome. We treated a 39-year-old woman who ingested 300 ml formalin in a suicidal attempt. Despite hemodialysis, death occurred after 23 h.

A Case of ${eta}-fluoroethyl$ Acetate Poisoning: Dong-Wun Shin, Jun-Seok Park, Ah-Jin Kim, Jun-Young Roh, Kyung-Hwan Kim; J Korean Soc Clin Toxicol. 2007;5(2):131-134. Published online December 31, 2007

Abstract PDF: The emergence of anticoagulant rodenticides in the 1950's resulted in an epochal reduction in the use of all other agents. It is estimated that anticoagulant rodenticides constitute 95 percent of all rodenticides now in use. However, the advent of rodent resistance to these agents has led to a return to use of some other non-anticoagulant types of rodenticides. Older non-anticoagulant rodenticides have been stored in basements, garages, and barns and are still in use in some regions of the United States and in other countries. We report a case of non-anticoagulant rodenticide (beta-fluoroethyl acetate) poisoning.

The Survey of Intoxication in the Two Hospitals of the City of Goyang: Kyung-Hwan Kim, Jun-Soek Park, Dong-Wun Shin, Jun-Young Rho, Hey-Jin Kim, Hong-Du Gu, Jin-Kyung Cho, Ah-Jin Kim; J Korean Soc Clin Toxicol. 2006;4(1):25-31. Published online June 30, 2006

Abstract PDF: Purpose: In the year of 2005, it enforced the basic study for establishing program of Poison Control Center by National Institute of Toxicologic Research. The object of our survey is to analyze the characteristics of intoxication from the City of Goyang by same protocol. Methods: We retrospectively reviewed the data of medical records of the intoxication patient in the two hospitals of the Goyang from 2004 June 1st to 2005 May 31th. The investigation protocol applied the TESS report form which was used from the Basic study for establishing program of Poison Control Center. Results: The intoxication patients were total 269 persons, the patients of A hospital were 184 persons, B hospital were 185 persons. The most common intoxication materials were medicines, in afterwords it was an agricultural chemical. The most common place of intoxication was the home. The intentional suicidal attempts in the reason of intoxication were 51.2%. The rate of the patients who discharges from the emergency department was 50.4% and death rate was 4.3%. Conclusion: We concluded that the continuous and systemic report and analysis should be accomplished from the Goyang area.

Two Cases of Mad-Honey Poisoning with Cardiovascular Symptom: Young-Gil Ko, Kyung-Hwan Kim, Ah-Jin Kim, Dong-Wun Shin, Jun-Soek Park, Jun-Young Roh, Ji-Young Ahn; J Korean Soc Clin Toxicol. 2006;4(1):78-81. Published online June 30, 2006

Abstract PDF: Mad-honey poisoning is mainly brought about by the honey imported from Napal, Turkey, Brazil and other parts of Europe. This mad honey is extracted from Ericaceae plants of Rhododendron species and contains grayanotoxins that causes poisoning. These toxic compounds exert a specific stimulatory action on membrane permeability to Na+ions in various excitable tissues and cause depolarization of cell membranes. The toxic effects of grayanotoxins contained honey are mainly cardiovascular disturbances with bradycardia, cardiac arrhythmia, hypotension. There are Other symptoms like nausea, vomiting, salivation, dizziness, weakness and loss of consciousness. The precise amount for a toxic dose is not known. In general the severity of the honey poisoning depends on the amount ingested. Two cases of mad-honey poisoning are described here. Both patients showed bradycardia and arterial hypotension after ingestion of honey which was brought from Nepal. They were recovered fully within 24 hours after administration of fluids and atropine sulphate.

Author index