- Two Cases of Acute Intoxication of Endosulfan
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Sang Jin Lee, Hye Young Jang, Eun Kyung Eo, Koo Young Jung
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J Korean Soc Clin Toxicol. 2003;1(1):47-50. Published online June 30, 2003
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 Abstract
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- Endosulfan, one of organochlorine insecticides, is $gamma$-aminobutyric acid (GABA) antagonist. In sufficient dose, this pesticide lower the seizure threshold and produce CNS stimulation, with resultant seizures, respiratory failure, and death. In patients with endosulfan intoxication, the first manifestation of toxicity is largely a generalized seizure without prodromal signs or symptoms. So the management of airway and seizure control are essential for survival and prognosis of intoxicated patients. We report two cases of acute endosulfan poisoning who manifest 'status epilepticus' similarly, but have different prognosis.
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KSCT
Korean Society of Clinical Toxicology