Journal of The Korean Society of Clinical Toxicology

Severe Liver Toxicity Caused by Amatoxin (Case Series): Joo-Hyun Suh, Sung-Jin Kim, Young-Kuk Chung, Woong-Gil Choi, Young-Se Kwon, Hyung-Keun Roh; J Korean Soc Clin Toxicol. 2006;4(1):73-77. Published online June 30, 2006

Abstract PDF: Poisoning with mushroom containing amatoxin may be a real medical emergency and is characterized by long incubation time lag, gastrointestinal symptoms, hepatotoxic phase and sometimes death. We report a family of parents and two children who ingested wild mushroom and recovered from varying degrees of hepatotoxicity. After eating cooked wild mushroom and its soup, they all developed abdominal pain, vomiting and diarrhea 11 hours later, Their liver enzymes reached peak level between 48 and 72 hours after the ingestion. Among the family members, 5-year-old girl showed the most severe hepatic toxicity of AST/ALT 14,099/13,176 IU/L. They were all treated with supportive measures including repeated activated charcoal and penicillin G and recovered from the hepatotoxicity between 7 and 28 days after the ingestion. Being based on the shape and a typical course of the amatoxin poisoning, we presume that this wild mushroom belongs to Amanita virosa.

A Case of Phalloides Syndrome where T-PLS(R)was used for Hemodynamic Support: Seong-Chun Kim, Kyu-Seok Kim, Gil-Joon Suh; J Korean Soc Clin Toxicol. 2004;2(2):133-136. Published online December 31, 2004

Abstract PDF: Phalloides syndrome has usually occurred after incidental mushroom ingestion. It is sometimes difficult to differentiate toxic mushrooms from edible ones, especially in lay person because of their morphological similarities. In Korea, Amanita virosa and Amanita subjunquillea have been reported as a cause of fulminant hepatic failure in mushroom poisoning (phalloides syndrome). We report a case of phalloides syndrome who came to death with fulminant hepatic failure even though we planned liver transplantation and used T-PLS(R) (Twin Pulse Life Support) for hemodynamic support while waiting for the donor.

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