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- Two Cases of Comatose Patients Presenting after Exposure to Hydrogen Sulfide Gas
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Hyun-Ho Ryu, Byeong-Guk Lee, Kyung-Woon Jeung, Tag Heo, Yong-Il Min
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J Korean Soc Clin Toxicol. 2009;7(1):26-31. Published online June 30, 2009
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Abstract
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- Hydrogen sulfide is a by-product of decayed organic material and is ubiquitously found as an ingredient of manufacturing reagents or as an undesirable by-product of the manufacturing or industrial processing. Hydrogen sulfide is a chemical asphyxiant and interferes with cytochrome oxidase and aerobic metabolism. It has thus been deemed an important cause of work-related sudden death. This gas is particularly insidious due to the unpredictability of its presence and concentration and its neurotoxicity at relatively low concentrations, causing olfactory nerve paralysis and loss of the warning odor. Here, we report two cases of comatose patients presenting after accidental exposure to hydrogen sulfide gas.
- Treatment with the Taylor Cyanide Antidote Package after Cyanide Poisoning: Case Report
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Beam-Gyu Cho, Han-Joo Choi, Yang-Soo Jang, Tae-Yang Shin, Kang-Hyun Lee, Sung-Oh Hwang, Hyun Kim
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J Korean Soc Clin Toxicol. 2007;5(1):57-60. Published online June 30, 2007
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Abstract
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- Cyanide has been well known from antiquity. Cyanide poisoning causes histotoxic hypoxia--inhibition of mitochondrial cytochrome oxidase with disruption of the ability of cells to use oxygen. The mortality rate is 95% within 30 minutes. Acute cyanide poisoning is mostly the result of attempted suicide, and because of the high doses typically employed it usually is lethal within minutes. Also acute cyanide poisoning leads to a very poor prognosis because medical personnel can't detect cyanide intoxication and so many hospital haven't antidote. We report two cases of cyanide poisoning which responded well to treatment with the Taylor cyanide antidote package.