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HOME > J Korean Soc Clin Toxicol > Volume 10(2); 2012 > Article
The Clinical Characteristics and Prognosis after Acute Ingestion of Glacial Acetic Acid
Gab-Yong Choi, Young-Gi Min, Yoon-Seok Jung, Joon-Pil Cho, Sang-Cheon Choi
Journal of The Korean Society of Clinical Toxicology 2012;10(2):91-96
DOI: https://doi.org/
Published online: December 31, 2012
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1Emergency Department, Ajou University School of Medicine
2Emergency Department, Ajou University School of Medicine
3Emergency Department, Ajou University School of Medicine
4Emergency Department, Ajou University School of Medicine
5Emergency Department, Ajou University School of Medicine

Purpose: A retrospective study with a literature review was conducted to identify the clinical characteristics and prognosis after the acute ingestion of glacial acetic acid. Methods: The medical records of 20 patients,who had presented to the emergency department of Ajou University Hospital complaining of the acute ingestion of glacial acetic acid between January 2006 and December 2011, were examined retrospectively. Results: Among the 172 patients admitted for caustics injury, 20 patients ingested glacial acetic acid. The mean age of the patients was $55{pm}23.5$, and the mean volume of the acid was $84.5{pm}71.3$ ml. The clinical features included 1) oral ulcers in 12 patients (63.2%), 2) respiratory difficulties in 11 patients (57.9%), 3) oliguria in 8 patients (42.1%), 4) renal toxicity in 7 patients (36.8%), 5) hepatic failure in 7 patients (36.8%), 6) disseminated intravascular boagulopathyin 7 patients (36.8%), 7) low blood pressure in 8 patients (42.1%), and 8) mental changes in 9 patients (47.4%). Ten patients required endotracheal intubation. Nine patients were admitted to the intensive care unit, and 5 patients expired. Conclusion: The ingestion of glacial acetic acid can cause severe symptoms, such as metabolic acidosis, multiple organ failure and upper airway swelling frequently and has a high mortality rate. Therefore, aggressive treatment, including endotracheal intubation, should be considered at the early stages.

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JKSCT : Journal of The Korean Society of Clinical Toxicology