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HOME > J Korean Soc Clin Toxicol > Volume 2(2); 2004 > Article
Paraquat Poisoning by Skin Absorption
Jong Oh Yang, Hyo Wook Gil, Eun Young Lee, Sae Yong Hong
Journal of The Korean Society of Clinical Toxicology 2004;2(2):101-105
DOI: https://doi.org/
Published online: December 31, 2004
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1Department of Internal Medicine, Soonchunhyang University, Institute of Pesticide Poisoning, Soonchunhyang University Cheonan Hospital
2Department of Internal Medicine, Soonchunhyang University, Institute of Pesticide Poisoning, Soonchunhyang University Cheonan Hospital
3Department of Internal Medicine, Soonchunhyang University, Institute of Pesticide Poisoning, Soonchunhyang University Cheonan Hospital
4Department of Internal Medicine, Soonchunhyang University, Institute of Pesticide Poisoning, Soonchunhyang University Cheonan Hospital

Purpose: Paraquat is the most commonly used herbicide in Korea. Exposure to paraquat through the skin has resulted in local irritation or inflammation of varying degree, sometimes severe. The purpose of this study was to review the patients with paraquat poisoning by skin absorption. Methods: We analysed retrospectively the clinical and laboratory findings of 45 patients with paraquat poisoning after dermal exposure, who were admitted to Soonchunhyang University Cheonan Hospital from January 1999 to December 2003. Results: Among 870 cases of paraquat poisoning, 45 cases were exposed to paraquat through the skin. The peak incidence was the fifth decade($40\%$). The clinical symptoms were pain, pruritus, nausea, and vomiting. The major skin lesions were generalized vesicobullae and necrotic erosion in face, scrotum, trunk, upper and lower extremities and etc. All patients were survived after skin contact or inhalation of paraquat. Conclusion: This study illustrates the extreme toxicity of paraquat and demonstrates that lethal quantities of paraquat may be absorbed if repeated exposure to it. Stricter precautions, including the mandatory use of protective clothing, should be recommended whenever this material is used.

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