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HOME > J Korean Soc Clin Toxicol > Volume 14(1); 2016 > Article
A Case of Aconite Poisoning Successfully Recovered after Intravenous Fat Emulsion Therapy
Hee Jun Shin, Hoon Lim
Journal of The Korean Society of Clinical Toxicology 2016;14(1):60-65
DOI: https://doi.org/
Published online: June 30, 2016
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1Department of Emergency Medicine, College of Medicine, Soon Chun Hyang University Hospital
2Department of Emergency Medicine, College of Medicine, Soon Chun Hyang University Hospital

Aconitum is a genus of various species of flowering plants that belongs to the Family Ranunculaceae. Most Aconitum sp. have extremely toxic alkaloid substances such as aconitine, mesaconitine and hypaconitine. Among these substances, aconitine can cause fatal cardiotoxicity by activating sodium channels followed by calcium channels in myocardial cells. Even though there have been various therapeutic plans suggested comprising antidotes based on diverse case reports and studies, there is no confirmatory treatment protocol for aconite poisoning. Here, we report an aconite poisoning patient who had refractory ventricular tachyarrhythmia that did not respond to intravenous amiodarone therapies even though they were sustained for over 2 hours, but showed successful recovery following intravenous fat emulsions (IFE) therapy.

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JKSCT : Journal of The Korean Society of Clinical Toxicology