Skip Navigation
Skip to contents

JKSCT : Journal of The Korean Society of Clinical Toxicology

OPEN ACCESS
SEARCH
Search

Articles

Page Path
HOME > J Korean Soc Clin Toxicol > Volume 18(2); 2020 > Article
Initial Serum Ammonia as a Predictor of Mortality in Patients with Acute Glufosinate Ammonium Herbicide Poisoning
Eun Na Ko, Dong Hoon Kim, Soo Hoon Lee, Jin Hee Jeong, Sang Bong Lee, Aejin Sung, Ja Hyoen Suh, Changwoo Kang
Journal of The Korean Society of Clinical Toxicology 2020;18(2):136-140
DOI: https://doi.org/10.22537/jksct.2020.18.2.136
Published online: December 31, 2020
  • 155 Views
  • 4 Download
  • 1 Crossref
  • 0 Scopus
1Department of Emergency Medicine, Gyeongsang National University School of Medicine
2Department of Emergency Medicine, Gyeongsang National University School of Medicine
3Department of Emergency Medicine, Gyeongsang National University School of Medicine
4Department of Emergency Medicine, Gyeongsang National University School of Medicine
5Department of Emergency Medicine, Gyeongsang National University School of Medicine
6Department of Emergency Medicine, Gyeongsang National University School of Medicine
7Department of Emergency Medicine, Gyeongsang National University School of Medicine
8Department of Emergency Medicine, Gyeongsang National University School of Medicine

Purpose: The association of the initial serum ammonia level with in-hospital mortality in patients with acute glufosinate-ammonium herbicide poisoning was studied. Methods: This retrospective cohort study was conducted between March 2012 and August 2019 in the emergency department after glufosinate-ammonium herbicide poisoning. Survivors and non-survivors were analyzed using a Mann-Whitney U test and Fisher's exact test. Multivariate logistic regression analysis was performed to determine the independent risk factors for mortality. Results: One hundred and six patients were enrolled; 11 died, yielding a mortality of 10.4%. The serum bicarbonate level was significantly lower in the non-survival group than the survival group. Age, serum ammonia, blood urea nitrogen, creatinine levels, SOFA score, and APACHE II score were significantly higher in the non-survival group than the survival group. Age, serum ammonia, and creatinine level were independent risk factors for mortality in multivariate logistic regression analysis. Conclusion: The initial serum ammonia level is associated with mortality in patients with acute glufosinate herbicide poisoning.

Related articles

JKSCT : Journal of The Korean Society of Clinical Toxicology