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HOME > J Korean Soc Clin Toxicol > Volume 3(2); 2005 > Article
A Case of Acute Intoxication with Glyphosate and Oxyfluorfen Containing Powder Herbicide ($Daejangun^{(R)}$)
Seung Hee Lee, Kum Ho Yi, Sung-Soo Yoo, Heung-Keun Roh
Journal of The Korean Society of Clinical Toxicology 2005;3(2):110-113
DOI: https://doi.org/
Published online: December 31, 2005
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1Department of Internal Medicine, Inha University Hospital
2Department of Internal Medicine, Inha University Hospital
3Department of Internal Medicine, Inha University Hospital
4Department of Internal Medicine, Inha University Hospital

Glyphosate containing herbicides are an alternative to paraquat and have been widely used with increasing frequency in suicide attempts throughout Asia. It is an organophosphorus compound that is not a cholinesterase inhibitor. Daejangun powder consists of glyphosate ammonium, surfactant and another herbicide, oxyfluorfen. A 60-year-old man ingested about 300 g of Daejangun powder with 500 ml of water in a suicide attempt. He was brought to emergency room 6 hours after the ingestion and showed severe metabolic acidosis (pH 6.75), marked leukocytosis (WBC 35,800/$mm^3$), hypoglycemia (glucose 13 mg/dL) and increased liver enzymes (AST/ALT 1,683/418 IU/L). Later he developed aspiration pneumonia, acute renal failure and hyperchloremic acidosis. Upper gastrointestinal endoscopy which performed 5 days after the ingestion revealed corrosive injuries (grade 1) in both esophagus and stomach. However, intensive treatment with supportive measures improved the abnormal findings almost completely 4 weeks after the ingestion.

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JKSCT : Journal of The Korean Society of Clinical Toxicology