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HOME > J Korean Soc Clin Toxicol > Volume 4(1); 2006 > Article
The Effect of Hemoperfusion on Plasma Concentration of Toxins in Acute Pesticide Poisoned Patients
Hyo-Wook Gil, Jong-Oh Yang, Eun-Yong Lee, Sae-Yong Hong
Journal of The Korean Society of Clinical Toxicology 2006;4(1):1-6
DOI: https://doi.org/
Published online: June 30, 2006
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1Institute of Pesticide Poisoning, Soonchunhyang University Cheonan Hospital
2Institute of Pesticide Poisoning, Soonchunhyang University Cheonan Hospital
3Institute of Pesticide Poisoning, Soonchunhyang University Cheonan Hospital
4Institute of Pesticide Poisoning, Soonchunhyang University Cheonan Hospital

Purpose: Hemoperfusion is an effective modality of extracorporeal elimination of toxins in acutely poisoned patients. We evaluated the effect of hemoperfusion on plasma concentration of toxins in patients exposed to certain pesticides. Methods: Eleven patients who were acutely exposed to pesticides participated in our study. We measured plasma pesticide concentration from the whole blood obtained by arterial and venous sources by gas chromatography. Results: The plasma concentrations of only 3 patients was measured. Methidation clearance by hemoperfusion was 82.2%, fenitrothion was 23%, and endosulfan was 0% Conclusion: Measurement of plasma organophosphate concentration is not a practical application. Our results suggest that hemoperfusion is applicable in patients with pesticide intoxication according to clinical status.

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JKSCT : Journal of The Korean Society of Clinical Toxicology