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HOME > J Korean Soc Clin Toxicol > Volume 13(1); 2015 > Article
A Case of Podostroma Cornu-Damae Intoxication Induced Pancytopenia and Skin Desquamation: Successful Treatment with Granulocyte Colony Stimulation Factor (G-CFS)
Jung Seok Kim, Gyu Won Kim, Jae Il Chung, Myoung Ki Sim, Ki Chul Yoon, Yong Hoon Choi, Ha Ram Yi, In Zoo Choi, Chan Sup Shim, Joung Ho Han
Journal of The Korean Society of Clinical Toxicology 2015;13(1):50-54
DOI: https://doi.org/
Published online: June 30, 2015
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1Department of Internal Medicine, Sahmyook Seoul Hospital
10Department of Internal Medicine, Chungbuk National University College of Medicine
2Department of Internal Medicine, Sahmyook Seoul Hospital
3Department of Internal Medicine, Sahmyook Seoul Hospital
4Department of Internal Medicine, Sahmyook Seoul Hospital
5Department of Internal Medicine, Sahmyook Seoul Hospital
6Department of Internal Medicine, Sahmyook Seoul Hospital
7Department of Internal Medicine, Sahmyook Seoul Hospital
8Department of Internal Medicine, Sahmyook Seoul Hospital
9Digestive Disease Center, Konkuk University Medical Center

Podostroma cornu-damae is a rare species of fungus belonging to the Hyocreaceae family. Its fruit body is highly toxic, as it contains trichothecene mycotoxins. The morphology is similar to that of immature Ganoderma lucidum, making identification difficult for non-experts. We experienced such a case of a 56- year-old male who picked and consumed podostroma cornu-damae, and consumed. Later that day, he developed digestive system symptoms, including nausea, vomiting, and abdominal pain. He presented to the emergency room (ER), there were no abnormal physical findings, symptoms improved after gastric lavage, and the patient voluntarily discharged himself on the same day. The following day, as the symptoms gradually deteriorated, he was admitted via the ER. He was presented with severe pancytopenia, alopecia, desquamation of skin, and acute renal failure. He recovered without any complications after conservative care, antibiotics therapy, and granulocyte colony stimulating factor administration. The most commonly reported complications of podostroma cornu-damae intoxication were reported pancytopenia, infection, disseminated intravascular coagulation, acute renal failure, etc. since Prevention is especially important because its toxicity can be lethal and there is no particular treatment to date, prevention is especially important. Promotion and education for the public are needed.

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JKSCT : Journal of The Korean Society of Clinical Toxicology